“Quantum of Solace” (2008) begins immediately after “Casino Royale” - with James Bond driving a dark grey Aston Martin DBS V12 along the mountain roads of Lake Garda, Italy - while being fiercely pursued by Spectre agents in black Alfa Romeo 159s.  The scene was shot on location along the narrow, winding roads of Lake Garda, the Limone Sul Garda tunnels, and a marble quarry in Carrara, Italy.  The sequence was notoriously dangerous to film - seven identical Aston Martin DBS models were destroyed - and a stunt driver was seriously injured when an Alfa plunged into Lake Garda.
How they shot it video here